MyBioSource.com's Ubiquitin Conjugation Factor E4 B Rabbit mAb is a Rabbit monoclonal antibody. The Ubiquitin Conjugation Factor E4 B Rabbit mAb Antibody was generated using UBE4B as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot.
Description
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (By similarity). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (PubMed:17369820)