The [KO Validated] KEAP1 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PIP5K1A. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] KEAP1 Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene