The Rabbit Anti-ErbB-3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ERBB3. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ErbB-3 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134)