G6PD Polyclonal Antibody from MyBioSource.com

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G6PD Polyclonal Antibody

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The G6PD Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to G6pd. This antibody recognizes Human, and Mouse antigen. The G6PD Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.

Description

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene