The Lamin A/C Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Lamin A/C, and LMNA. This antibody recognizes Human, Mouse, and Rat antigen. The Lamin A/C Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Recruited by DNA repair proteins XRCC4 and IFFO1 to the DNA double-strand breaks (DSBs) to prevent chromosome translocation by immobilizing broken DNA ends