The Rabbit Anti-Bcl-x Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BCL2 like 1, and BCL2L1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Bcl-x Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X (S) promotes apoptosis