The Integrin alpha2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITGA2. This antibody recognizes Human, Mouse, and Rat antigen. The Integrin alpha2 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2: ITGB1 acts as a receptor for Human echoviruses 1 and 8