MyBioSource.com's Rabbit Anti-Tau Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-Tau Antibody was generated using MAPT as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3)