CRTC3 Rabbit mAb from MyBioSource.com

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CRTC3 Rabbit mAb

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The CRTC3 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to CRTC3. This antibody recognizes Human, Mouse, and Rat antigen. The CRTC3 Rabbit mAb Antibody has been shown to work in the following applications: Western Blot.

Description

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)