The Rabbit Anti-Collagen IV Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to COL4A1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Collagen IV Antibody has been shown to work in the following applications: Immunofluorescence.
Description
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1 2 and p38 MAPK activation. Ligand for alpha1 beta1 integrin (By similarity)