MyBioSource.com's Rabbit Anti-Histone H4 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Rabbit Anti-Histone H4 Antibody was generated using H4 clustered histone 15, H4 clustered histone 8, H4 histone 16, H4-16, H4C15, and H4C8 as the antigen and it reacts with Human, Mouse, Rat, and Non-Human Primate.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling