The AML1 (RUNX1) Conjugated Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RUNX family transcription factor 1, and RUNX1. This antibody recognizes Human antigen. The AML1 (RUNX1) Conjugated Antibody has been shown to work in the following applications: Other.
Description
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation