MyBioSource.com's Integrin alpha6 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Integrin alpha6 Polyclonal Antibody was generated using ITGA6 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Integrin alpha-6/beta-1 (ITGA6: ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6: ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6: ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6: ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6: ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6: ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464)