MyBioSource.com's Septin 7 Rabbit mAb is a Rabbit monoclonal antibody. The Septin 7 Rabbit mAb Antibody was generated using Septin 7, and SEPTIN7 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830)