The Rabbit Anti-PERK Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EIF2AK3. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-PERK Antibody has been shown to work in the following applications: Immunofluorescence.
Description
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function