MyBioSource.com's Rabbit Anti-HIST1H2BC Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The Rabbit Anti-HIST1H2BC Antibody was generated using H2B clustered histone 10, H2B clustered histone 5, H2BC10, H2BC5, and H2BC7 as the antigen and it reacts with Human.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling