The Rabbit Anti-ARRB2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ARRB2, and Arrestin beta 2. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ARRB2 Antibody has been shown to work in the following applications: Immunofluorescence, and Immunohistochemistry.
Description
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
This product can be used in analytical tools such as IHC, Immunofluorescence