MyBioSource.com's Rabbit Anti-HIST1H3A Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The Rabbit Anti-HIST1H3A Antibody was generated using H3 clustered histone 1, H3 clustered histone 6, H3C1, and H3C6 as the antigen and it reacts with Human.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling