The Rabbit Anti-SH-PTP1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to protein tyrosine phosphatase non-receptor type 6, and PTPN6. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-SH-PTP1 Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis