MyBioSource.com's Rabbit Anti-Lymphocyte Activation Gene 3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunofluorescence. The Rabbit Anti-Lymphocyte Activation Gene 3 Antibody was generated using LAG3 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4