The Cyclin D1 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Ccnd1, and Cyclin D1. This antibody recognizes Human, Mouse, and Rat antigen. The Cyclin D1 Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals