MyBioSource.com's SMCHD1 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The SMCHD1 Rabbit pAb Antibody was generated using SMCHD1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells (PubMed:23143600)