The Anti-NKG2D [6E5A7], Rabbit IgG Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to KLRK1, and KLRC4-KLRK1. This antibody recognizes Human antigen. The Anti-NKG2D [6E5A7], Rabbit IgG Antibody has been shown to work in the following applications: Block/Neutralize/Inhibit, and Flow Cytometry.
Description
The NKG2D (Natural Killer Group 2 Member D) protein is an activating receptor that enables NK and CD8 + T cells to recognize and eliminate infected or transformed endogenous cells. However, an incorrect regulation of this receptor on immune cells also appears to lead to the development of autoimmune diseases such as type I diabetes, celiac disease and RA.This antibody positively reacts with NKG2D on CD8-positive T cells and to CD56-positive natural killer cells. The binding was confirmed FACS analysis (Steigerwald, 2008)