The Rabbit Anti-CAV1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CAV1, and Caveolin 1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-CAV1 Antibody has been shown to work in the following applications: Western Blot.
Description
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
This product can be used in analytical tools such as Western Blot