MyBioSource.com's Rabbit Anti-CD11b c Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunofluorescence. The Rabbit Anti-CD11b c Antibody was generated using ITGAM as the antigen and it reacts with Human, Mouse, and Rat.
Description
Integrin alpha-M beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain