The Rabbit Anti-HEXA Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HEXA. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-HEXA Antibody has been shown to work in the following applications: Immunohistochemistry.
Description
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
This product can be used in analytical tools such as IHC