The Rabbit Anti-CHRFAM7A Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CHRFAM7A. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-CHRFAM7A Antibody has been shown to work in the following applications: Western Blot.
Description
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
This product can be used in analytical tools such as Western Blot