MyBioSource.com's IL-18R Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The IL-18R Polyclonal Antibody was generated using IL18R1, and Interleukin 18 Receptor 1 as the antigen and it reacts with Human.
Description
Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:14528293, PubMed:25261253, PubMed:25500532). Involved in IL18-mediated IFNG synthesis from T- helper 1 (Th1) cells (PubMed:10653850). Contributes to IL18- induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity)