The Rabbit anti p53 (pSer9) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TP53, and tumor protein p53. This antibody recognizes Human antigen. The Rabbit anti p53 (pSer9) Antibody has been shown to work in the following applications: Western Blot.
Description
Rabbit anti p53 (pSer9) antibody recognizes the p53 tumor suppressor protein, also known as cellular tumor antigen p53 or NY-CO-13, when phosphorylated at serine 9. The p53 protein is important in multicellular organisms, where it regulates cell cycle progression to allow DNA repair or apoptosis in the case of irreparably damaged cells and thus functions as a tumor suppressor, involved in preventing cancer (Haupt et al. 2003). Mutations in the p53 gene are found in approximately half the cases of human cancer (Joerger and Fersht 2007).
p53 is phosphorylated at serine 9 by CK1-delta (Higashimoto et al. 2000)