The Rabbit Anti-NFkappaB-p100/p52 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NFKB2. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-NFkappaB-p100/p52 Antibody has been shown to work in the following applications: Other.
Description
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth