The MYBPC3 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MYBPC3, and myosin binding protein C3. This antibody recognizes Rat antigen. The MYBPC3 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy