The FOLR2 Antibody FITC from MyBioSource.com is a Rabbit Polyclonal antibody to FOLR2. This antibody recognizes Mouse, and Rat antigen. The FOLR2 Antibody FITC has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Overview: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Structure: Belongs to the folate receptor family.
Expression: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues