The D4DR Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to dopamine receptor D4, and DRD4. This antibody recognizes Human, Mouse, and Rat antigen. The D4DR Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity)