The Rabbit Anti-Cleaved-Caspase-5 p10 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP5, and Caspase 5. This antibody recognizes Human antigen. The Rabbit Anti-Cleaved-Caspase-5 p10 Antibody has been shown to work in the following applications: Western Blot.
Description
Mediator of programmed cell death (apoptosis). During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation (PubMed:28314590). Thiol protease that acts as a mediator of programmed cell death (PubMed:29898893, PubMed:28314590). Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin- D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis (PubMed:29898893)