The [KO Validated] DGUOK Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NDRG1. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] DGUOK Rabbit pAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene