The Rabbit Anti-SPTLC1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SPTLC1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-SPTLC1 Antibody has been shown to work in the following applications: Immunohistochemistry.
Description
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
This product can be used in analytical tools such as IHC