The RNF43 Antibody, Biotin conjugated from MyBioSource.com is a Rabbit Polyclonal antibody to RNF43. This antibody recognizes Human antigen. The RNF43 Antibody, Biotin conjugated has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone