The Rabbit Anti-SQSTM1/p62 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SQSTM1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-SQSTM1/p62 Antibody has been shown to work in the following applications: Other.
Description
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone