The GPR75 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GPR75. This antibody recognizes Human, and Mouse antigen. The GPR75 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor