MyBioSource.com's TriMethyl-Histone H3-K27 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Precipitation, ChIP, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot. The TriMethyl-Histone H3-K27 Rabbit pAb Antibody was generated using H3-4, and H3.4 histone as the antigen and it reacts with Human, Mouse, Rat, Amoeba/Protozoa, Bacteria/Archaea, Bovine, C. elegans/Worm, Canine, Chicken/Bird, Donkey, Drosophila/Arthropod, Feline, Goat, Guinea Pig, Hamster, Horse, Mollusc, Non-Human Primate, Plant, Porcine, Reptile, Rabbit, Sheep, Virus, Xenopus/Amphibian, Yeast/Fungi, Zebrafish/Fish, Other Invertebrate, and Other Mammalian.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling