The CD3 antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The CD3 antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
The UCHT1 monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation