The MRCKalpha Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CDC42BPA. This antibody recognizes Human, Mouse, and Rat antigen. The MRCKalpha Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:9418861, PubMed:9092543). Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:11399775). May play a role in TFRC-mediated iron uptake (PubMed:20188707). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity)