The Rabbit Anti-Histone H3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to H3 clustered histone 1, H3 clustered histone 6, H3C1, and H3C6. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Histone H3 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers