MyBioSource.com's Anti-Hu CD84 Purified is a Mouse monoclonal antibody. The Anti-Hu CD84 Purified Antibody was generated using CD84 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunoprecipitation.
Description
CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated