MyBioSource.com's Anti-Mouse LPAM-1 APC is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mousealpha4beta7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha4 and the 130 kDa beta7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha4beta7 integrin heterodimer. alpha4beta7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the alpha4beta7 induces the alpha4beta7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion