The Histone H4 (Tri Methyl K20) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to H4 clustered histone 8, H4 histone 16, H4-16, and H4C8. This antibody recognizes Human, Mouse, and Rat antigen. The Histone H4 (Tri Methyl K20) Rabbit pAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling