The IFN beta Antibody from MyBioSource.com is a Mouse Monoclonal antibody to IFNB1, and interferon beta 1. This antibody recognizes Human antigen. The IFN beta Antibody has been shown to work in the following applications: Block/Neutralize/Inhibit, Immunohistochemistry, Immunohistochemistry - frozen, and Western Blot.
Description
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-alpha is an acid-stable molecule that signals through IFN-alpha/betaR, which is also used by IFN-beta. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-alpha contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-beta is a 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFN-beta has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry