The Anti-Mouse CD8a Purified Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Mouse antigen. The Anti-Mouse CD8a Purified Antibody has been shown to work in the following applications: Flow Cytometry, Functional Assay, and Immunohistochemistry.
Description
The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b.CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells