The CXCR4 Rabbit Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CXCR4. This antibody recognizes Human, Mouse, and Rat antigen. The CXCR4 Rabbit Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized