The Rabbit Anti-ADRBK1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GRK2. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ADRBK1 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
This product can be used in analytical tools such as Western Blot, IHC